Familial Adenomatous Polyposis- Presenting with Partial Bowel Obstruction

Familial adenomatous polyposis ia an autosomal dominant disorder that is responsible for 0.5% of all colorectal cancer. Patients will develop hundreds to thousands of colonic polyp in their second decades of life. The life time risk of developing colorectal cancer is 100% at the median age of 39 years. Extra intestinal manifestations are rare and mostly are benign. Family history of colorectal cancer is common in FAP. Screening of FAP family members should begin with age of 10-12 years. Management option includes total proctocolectomy with end ileostomy, total colectomy with ileorectal anastamosis, and total proctocolectomy and ileal pouch anal anastamosis.Here is a report of rare case of familial adenomatous polyposis presented with intermittent partial bowel obstruction and managed with total proctocolectomy with end ileostomy and reviewed the literature and discussed tumorogenesis , screening recommendation and management options.